Category Archives: science translational medicine
Indiana University paper about lung transplantation retracted after misconduct finding
After a finding of data manipulation, the corresponding author of a 2014 paper by a team of researchers at Indiana University has retracted the work. Here’s the notice in Science Translational Medicine: Science Translational Medicine is retracting the Research Article “The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation” by Weber et … Continue reading Indiana University paper about lung transplantation retracted after misconduct finding
Posted by in AAAS, science translational medicine
“Data had been manipulated:” Science Translational Medicine retracts paper
Science Translational Medicine has retracted a paper by researchers based in Switzerland, after an investigation concluded two figures had been manipulated. The investigation occurred at the University of Basel. It’s not clear what prompted it, but the paper has been discussed at length on PubPeer. After the investigation concluded two figure panels included manipulated data, the last […]
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Widely used brain tumor cell line may not be what researchers thought it was
Nearly 50 years ago, researchers in Uppsala, Sweden used cells from a patient to establish a brain tumor cell line that has become widely used. But a new study suggests that the most common source of that cell line used by scientists today may not be derived from that original patient’s tumor, raising questions about […]
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Posted by in science translational medicine, wrong reagents
What does “reproducibility” mean? New paper seeks to standardize the lexicon
What is the difference between “reproducible” and “replicable”? And how does each relate to results that are “generalizable” and “robust”? Researchers are using these terms interchangeably, creating confusion over what exactly is needed to confirm a scientific result, argues a new paper published today in Science Translational Medicine. Here’s how the US National Science Foundation (NSF) […]
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Posted by in AAAS, daniele fanelli, not reproducible, science translational medicine, united states
Downstream effects: Comment on retracted narcolepsy paper retracted
The recent retraction of a paper in Science Translational Medicine reporting “one of the biggest things to happen” in narcolepsy research has claimed a bystander: A letter that commented on the no-longer-landmark article. The authors of the letter are with GlaxoSmithKline’s vaccine division. Here’s the new notice: Our Letter “Comment on ‘CD4+ T cell autoimmunity […]
Authors retract paper “confirming” that narcolepsy is an autoimmune disease
A group of researchers at Stanford and elsewhere is retracting a 2013 paper that another scientist told Nature was “one of the biggest things to happen in the narcolepsy field for some time.” The Science Translational Medicine paper caused a buzz because it claimed to show that narcolepsy was an autoimmune disease. Here’s the notice: A.K. […]