Moving data at the speed of a virus

Scientist reviews results from testing

by Rachel Shepherd, specialist, Informatics, APHL

The public health system serves as the backbone to our nation’s health and safety; there is nothing more collectively critical than making sure we are prepared to respond to threats. When a public health crisis like COVID-19 strikes, laboratories need to get mechanisms in place fast to test for a new pathogen. But there’s another, equally important side to that story. Without the technical infrastructure to send and receive data, and without agreed-upon language to communicate information, there could be no comprehensive response or strategy. In other words, you can build a car to get from Point A to Point B, but you won’t get very far if there are no roads. This is a story about roads.

In 2008, APHL built the APHL Informatics Messaging Services (AIMS) Platform, a messaging service for public health laboratories and agencies to transmit their influenza results to the US Centers for Disease Control and Prevention (CDC) for surveillance. Over time, AIMS went from having a handful of laboratories signed on to establishing connections with every state in the country, making, for the first time in history, near real-time national flu surveillance possible.

Today, most of the nation’s public health network—more than 200 public health laboratories and agencies, clinical and commercial labs, hospitals and medical providers, and federal agencies—uses AIMS to exchange critical health data, sending more than 25 million messages per month. AIMS now serves as a “super highway” on which testing data for several major public health initiatives flow, providing the means for national surveillance. While its functionality continues to expand, at its core AIMS ensures that important data travel fast into the right hands so that it can be actionable when it matters most.

When cases of COVID-19 began cropping up in the US, public health laboratories began getting testing up and running successfully. The public heard about assays not working, testing backlogs, overwhelmed staff, and reagent shortages. What the public didn’t hear about were the crises averted. Amidst all of the pandemic chaos, there has been at least one major positive: we already had a national data messaging platform that connects all of public health. No infrastructure had to be built; it’s been in place and growing since 2008.

When public health entities connect to AIMS, they enable faster transmission of a higher volume of data for surveillance or trend analysis. When information is exchanged through AIMS, what used to take days now takes minutes, and time saved—whether in a pandemic or in the routing and sharing of test orders and results—translates to lives saved. Doctors can make better informed decisions about patient-care when they have timely access to test results, and epidemiologists can analyze data to identify emergent threats before they become crises.

In addition to transporting data, AIMS also has portal services that automatically transform and translate data to different message formats and standards; in other words, users are able to communicate through AIMS, even if they are speaking different languages. AIMS converts messages and makes them readable to the receiver. Because of the sensitive nature of the data that flows through AIMS, AIMS takes security seriously and meets some of the most stringent security standards in the country.

AIMS also allows multiple users to take advantage of shared resources—for instance, laboratories can maintain one route on AIMS for all of their trading partners rather than having to establish and maintain an individual route with each. This is a major benefit to AIMS users. Typically, each laboratory would have to set up a connection with every entity with whom they exchange data—clinical laboratories, hospitals, public health agencies. When laboratories or agencies are on AIMS, they can condense all of their routes into a single connection and significantly reduce time and effort that would otherwise have to be dedicated to each.

In just over a month’s time, APHL worked with every single public health laboratory and agency to make sure they were able to electronically send their COVID-19 requests and results to CDC. They also worked on developing COVID-specific vocabulary and coding for testing so that when laboratories started conducting testing, they were all using the same terminology from the start. This means that all results sent to CDC were standardized—no effort or time had to be spent deciphering and comparing reports across laboratories to try and synthesize.

APHL’s job is to build and leverage technical solutions that will ease the burden on laboratories, not only for this response effort and a future of unknown threats, but to improve and simplify data exchange for public health at large on a day-to-day basis. When CDC launched its Data Modernization Initiative, it placed the urgent need for meaningful data to be sent and received faster; public health depends on information and results to be communicated quickly for surveillance, intervention and treatment. Time is critical. With the response to COVID-19, there is now a national recognition and comprehensive effort to modernize tools, technology, strategy and perceptions around data.

COVID-19 may very well prove to be a once-in-a-lifetime public health emergency. It may not. All we know is that we don’t know, and that our collective health and safety depends on having an efficient exchange mechanism in place to surveil, protect and be prepared.

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UberOps CEO talks public health in the cloud

UberOps CEO talks public health in the cloud | www.APHLblog.org

In a very short time, Americans have become increasingly familiar with the cloud. Not the white fluffy ones in the sky, but the cloud where much of our day-to-day computing takes place. Even for people who aren’t familiar with the term, they likely are familiar with the concept of accessing internet-based files from anywhere. Photos taken on your smartphone might be automatically uploaded to a cloud-based storage system where you can view or download those photos on your laptop. Just as this technology has become valuable in our daily lives, it has become valuable in public health.

At this year’s APHL Annual Meeting, Eduardo Gonzalez Loumiet, CEO of UberOps, presented on public health in the cloud. We asked Eddie a few questions about the system that he has worked to develop along with APHL informatics and the value that this platform offers public health laboratories and ultimately the American public.

Learn more about AIMS — AIMS Platform: Outpacing Pathogens from the Cloud

In simple terms, what is the AIMS platform? What is the role of UberOps?

AIMS stands for the APHL Informatics Messaging Services Platform. AIMS was developed in 2008 as part of the Public Health Laboratory Interoperability Project (PHLIP) focused on influenza surveillance with the CDC.

AIMS is a secure, cloud based environment that accelerates the implementation of health messaging by providing shared services to aid in the transport, validation, translation and routing of electronic data.

The AIMS Platform has grown to a community of more than 85 trading partners involved in several use cases including ELR, Whole Genome Sequencing, ARLN and NMI. New use cases are being discovered every day.

UberOps is an APHL partner that develops and supports the AIMS Platform. We work on the deep technical aspects of AIMS. Our focus is on continuously securing the environment, trading partner onboarding, and ensuring trading partners have the information and tools to leverage AIMS Platform benefits.

Why should public health labs use a cloud-based system? What are the benefits? 

The benefits of using cloud computing have surpassed perceived risks. AIMS utilizes Amazon Web Services (AWS), the industry leader in Cloud computing. The benefits of cloud computing include:

  1. Security, high availability and reliability
  2. Centralized processing and message routing
  3. Real-time monitoring and audit systems
  4. Reduced message transport complexity
  5. Reduced data translation and transformation complexity
  6. Reduced development and support costs
  7. Flexible capacity infrastructure
  8. FISMA Moderate compliant applications
  9. FedRAMP compliant environment via the cloud provider
  10. Commitment to innovation and the future

Are public health laboratories the only labs using AIMS?

UberOps CEO talks public health in the cloud | www.APHLblog.org

AIMS was built to serve public health laboratories. Over the last 18-24 months the AIMS infrastructure has expanded capability to allow public health agencies and a select group of private laboratories to securely exchange data as well. We have also seen an increase in cross-jurisdictional ELR data exchange between agencies. AIMS has also been used to host other non-profit data, such as STEVE 2.0, which focuses on exchanging birth and death records between states. And AIMS is being used to process data for the first time in the cloud through virtual workstations for the whole genome sequencing project. We are excited for the emerging possibilities!

Is it secure? How do I know my information wont be stolen or misused?

The top priority for APHL and UberOps is a secure and compliant AIMS Platform. Stringent healthcare laws and regulations across jurisdictions are monitored on a regular basis, and revisited on a regular basis. The AIMS Platform is FISMA Moderate compliant, which requires a once per year third-party audit. In addition to the audit, the AIMS infrastructure is required to pass firewall penetration testing.

Each member of the AIMS Platform team attends yearly HIPAA privacy and security training. The AIMS dedicated security team uses advanced, real-time monitoring tools to proactively eliminate potential threats.

What does this mean for the public? Are there clear benefits for people in the community?

AIMS is an extension of everything our public labs represent in the United States. The ability to monitor and detect health threats quickly using a shared technology platform is an invaluable asset for the safety of all citizens. Preventing and/or predicting large expected (like influenza) and unexpected (like Zika) public health events is where the AIMS Platform serves our communities.

What does the future hold for AIMS?

APHL, UberOps and AIMS stakeholders are constantly looking to expand the functionality of the AIMS infrastructure. As the evolution of health data continues, we see new opportunities to assist with integrating data and providing a higher quality experience for trading partners, patients and citizens.

Our recent platform growth between public and private collaboration will continue, and we expect to expand AIMS application services (examples: Dashboards, Portals, LIMS), electronic case reporting and much more!

 

The post UberOps CEO talks public health in the cloud appeared first on APHL Lab Blog.

AIMS Platform: Outpacing Pathogens from the Cloud

AIMS Platform: Outpacing Pathogens from the Cloud | www.APHLblog.org

By Rachel Shepherd, associate specialist, Informatics, APHL

​​In a kindergarten classroom in Des Moines, a small boy begins to shiver uncontrollably. In a nursing home in Phoenix, a pneumonic grandmother fights for her life from a hospital bed. On a crowded metro car in Washington, DC, in the miniscule droplets of saliva from a man’s kind “Hello” to a stranger, it attacks. The flu. It comes every year as the months begin to shift into winter, returning slightly different than before, exploding and thriving, determined to wreak havoc. It descends upon the nation, preys upon us in our most vulnerable moments, and says, “This is my  year.”

In public health, every emerging threat—the flu, E. coli, Legionnaires’ disease, Ebola, Zika—is a race against time. What can scientists learn from these deadly pathogens, and more importantly, how fast? Lives depend on this data, on laboratories’ ability to track patterns, decipher mutations and to share, compare and build upon those findings—crowdsourcing at its finest and most critical.

Only a few years ago, a lab would manually enter its test results and fax them to CDC and other reference centers. Someone would receive the paper transmission and manually re-enter it. The process would take days. In that time, an outbreak could have spread. Lives could have been lost.

Time matters. But thanks to an APHL-CDC initiative, what used to take days can now take minutes. In 2008, public health labs recognized the need to share their data electronically. APHL worked hand in hand with informatics specialists at state labs and CDC to develop what was then known as the Route not Read (RnR) hub. This seemingly simple, but powerful approach sent public health data through a service that read the outside envelope of the electronic message and delivered it to the intended recipient without opening its contents.

Four years later, the increasing complexity and demands for public health data led to the development of the AIMS platform. Now in a cloud-based environment, AIMS has burgeoned over the years. The new environment accelerates the transmission of data and provides shared services, such as message validation translation, to labs and trading partners. Today, more than 85 organizations and institutions exchange data over AIMS, with more than 25 million messages transported to date.

The vital data exchanged on AIMS includes aggregated influenza test results from public health laboratories to CDC, vaccine-preventable disease reports, biological threat data, immunization data exchange among several public health jurisdictions, electronic laboratory reporting between hospitals and their jurisdictions, and whole genome sequencing through the Advanced Molecular Detection initiative. And AIMS is expanding again to offer electronic case reporting to connect laboratories and health agencies with CDC and with other data recipients nationwide.

Since its launch in 2012, the AIMS platform has equipped public health officials to monitor and respond rapidly to health threats, strengthened labs with shared resources and expedited delivery of time-sensitive health information to consumers. As the platform continues to gain traction, its contributions to the nation’s health infrastructure will be tremendous.

The post AIMS Platform: Outpacing Pathogens from the Cloud appeared first on APHL Lab Blog.