Come see NCBI at the ASM Microbe Conference 2022

The American Society of Microbiology (ASM) Microbe conference is back, and scheduled to take place in-person, June 9th-13th in Washington, D.C. NCBI staff member Dr. Michael Feldgarden will be recognized by ASM with an award for his research. Other NCBI staff will present posters on NCBI resources and will also be available at our booth … Continue reading Come see NCBI at the ASM Microbe Conference 2022

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Announcing Human Annotation Release 110

The annotation of human assemblies GRCh38.p14 and T2T-CHM13v2.0 We are happy to announce the first de novo annotation of human T2T-CHM13v2.0, the gap-less assembly generated by the T2T Consortium, and the full re-annotation of the human reference assembly, GRCh38.p14. We hope the results will serve both the needs of those eager to explore newly sequenced regions of the genome, including … Continue reading Announcing Human Annotation Release 110

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Venturing beyond the genes: New RefSeq Functional Elements publication!

If you’re curious about genome annotation beyond the genes, then read on! We previously blogged about our RefSeq Functional Elements resource, which provides annotation of experimentally validated, non-genic functional elements in human and mouse. Now, to kick off 2022, we’re delighted to announce a new publication in the January issue of Genome Research: Farrell CM, … Continue reading Venturing beyond the genes: New RefSeq Functional Elements publication!

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Bulk Sequence-Cytogenetic Conversion Service to be retired in April 2022

The Bulk Sequence-Cytogenetic Conversion Service tool at NCBI will be retired in April 2022. This tool obtained cytogenetic locations for a list of annotated genes, SNPs, or assembly coordinates from human, fruit fly, mouse, or rat genomes. It also obtained sequence coordinates for cytogenetic locations for these genomes. This web service will be retired due to low … Continue reading Bulk Sequence-Cytogenetic Conversion Service to be retired in April 2022

Announcing the RefSeq annotation of sheep ARS-UI_Ramb_v2.0!

The new reference assembly for sheep is now annotated! Assembly ARS-UI_Ramb_v2.0 is made of 142 scaffolds, a drop from 2,640 in the 2017 assembly Oar_rambouillet_v1.0. With a contig N50 of 43 Mb, ARS-UI_Ramb_v2.0 is 15 times more contiguous than the first assembly of the Rambouillet breed. Annotation Release 104 (AR 104) of ARS-UI_Ramb_v2.0 reflects these improvements. Nearly 200 … Continue reading Announcing the RefSeq annotation of sheep ARS-UI_Ramb_v2.0!

New RefSeq annotations for human, zebra finch, great white shark and more!

In May and June, the NCBI Eukaryotic Genome Annotation Pipeline released new annotations in RefSeq for 27 organisms. This release includes new annotations for human, zebra finch, golden eagle, sea urchin, snowfinch, Arctic fox, clawed frog, great white shark, and more: Alosa sapidissima (American shad) Anopheles merus (mosquito) Aquila chrysaetos chrysaetos (golden eagle) Aricia agestis (brown argus) … Continue reading New RefSeq annotations for human, zebra finch, great white shark and more!

Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!

We have re-annotated all RefSeq genomes for Escherichia coli, Mycobacterium tuberculosis, Bacillus subtilis, Acinetobacter pittii, and Campylobacter jejuni using the most recent release of PGAP. You will find that more genes now have gene symbols (e.g. recA). Your feedback indicated that the lack of symbols was an impediment to comparative analysis, so we hope that this improvement … Continue reading Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!

Announcing RefSeq Release 206!

RefSeq Release 206 is now available. This release includes the following: Updated human genome Annotation Release 109.20210514 Updated Annotation Release 109.20210514 is an update of NCBI Homo sapiens Annotation Release 109. The annotation report is available here. The annotation products are available in the sequence databases and on the FTP site. Other new eukaryotic genome … Continue reading Announcing RefSeq Release 206!

New RefSeq annotations for Siamese fighting fish, common toad, swan, platypus and more!

In March and April, the NCBI Eukaryotic Genome Annotation Pipeline released thirty-two new annotations in RefSeq for the following organisms: Aegilops tauschii (monocot) Amblyraja radiata (thorny skate) Anopheles arabiensis (mosquito) Anopheles coluzzii (mosquito) Bactrocera tryoni (Queensland fruit fly) Belonocnema kinseyi (wasp) Betta splendens (Siamese fighting fish) Bufo bufo (common toad) Cygnus olor (mute swan) Falco naumanni (lesser kestrel) … Continue reading New RefSeq annotations for Siamese fighting fish, common toad, swan, platypus and more!

New NCBI Datasets home and documentation pages provide easier access

NCBI Datasets, the new set of services for downloading genome assembly and annotation data (previous Datasets posts), has redesigned and reorganized web pages to make it easier to find and access the services and documentation you need. NCBI Datasets has a fresh new homepage (Figure 1) highlighting the types of data available through our tools. Available … Continue reading New NCBI Datasets home and documentation pages provide easier access