Improved Search Now Available Across NCBI Databases

Earlier this year, we announced the release of a new and improved search feature that interprets plain language to give better results for common searches. This feature, originally developed in NCBI Labs and later released on the NCBI All Databases search, is … Continue reading

Hey Professors! Get your free personal assistant — an NCBI Account!

Professors, we know you’re busy ­­— really, really busy.  You have to develop and teach your courses and labs, coordinate and run your journal clubs and seminars, direct your lab’s research efforts, write grants and publications, counsel and mentor your … Continue reading

Genes – way weirder than you thought

orcid.org/0000-0001-5816-9771 Pretty much everyone, at least in societies with access to public education or exposure to media in its various forms, has been introduced to the idea of the gene, but “exposure does not equate

CCDS release 22 for human is public in Gene

The Consensus Coding Sequence (CCDS) update that compares NCBI’s Homo sapiens annotation release 109 to Ensembl’s release 92 is now reflected in Gene. This update adds 894 new CCDS IDs, and adds 154 Genes into the human CCDS set. CCDS … Continue reading

Human annotation release 109 for GRCh38.p12 is available in RefSeq

You can now download human annotation release 109 on FTP or explore it in the Genome Data Viewer, in the Gene database, and with BLAST. Highlights in release 109: A total of 20,203 protein-coding genes and 17,871 non-coding genes were … Continue reading

Bioinformatics paper uses NCBI open data to analyze drug response

A study (PMID: 28158543) published in the July 2017 issue of Bioinformatics collects, classifies and analyzes single nucleotide variants (SNVs) that may affect response to currently approved drugs. They identified 2,640 SNVs of interest, most of which occur rarely in populations (minor … Continue reading

Expression teasers and indexing added to Gene

Last February, we added gene expression data to Gene. Now, you can access these data in a few new ways. Expression pattern “teasers” in Summary We’ve added a brief sentence describing the expression pattern to the Summary section. This teaser … Continue reading

Gene_orthologs file on Gene FTP site

For ease in accessing the orthology data subset, a new gene_orthologs FTP file has been created on the Gene FTP site. The file uses the same format as the gene_group file. As of January 31, 2018, the gene_group FTP file … Continue reading

5 NCBI articles in 2018 Nucleic Acids Research database issue

The 2018 Nucleic Acids Research database issue features several papers from NCBI staff that cover the status and future of databases including CCDS, ClinVar, GenBank and RefSeq. These papers are also available on PubMed. To read an article, click on … Continue reading

Updated HIV-1 interaction datasets in Gene

We recently updated the HIV-1 interaction datasets in Gene with data provided by the Southern Research Institute (SRI). The protein interactions dataset now has: 8,005 interactions, 16,215 interaction descriptions, 3,859 proteins encoded by 3,757 human genes, and 6,822 publications. The … Continue reading