A shadow was cast on a bone researcher’s work. What are journals doing about his papers?

Last year, a researcher cast doubt on a bone scientist’s clinical trials, suggesting some of the findings may not be legitimate. So what’s happened since? Since 2015, journals have retracted 14 papers by bone researcher Yoshihiro Sato, based at Mitate Hospital in Japan, for issues ranging from self-plagiarism, to problems with data, to including co-authors without their consent. […]

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“Elementary, My Dear Watson!” Clues Revealed About an Ancient Case of Leprosy

Unidentified remains found in the English countryside and all signs point to the untimely death of a young man. Researchers examined the bones of a supposed victim, which showed signs of leprosy, to search for clues about the arrival of … Continue reading »

The post “Elementary, My Dear Watson!” Clues Revealed About an Ancient Case of Leprosy appeared first on PLOS Blogs Network.

Can penguins tell us how far the Cretaceous diving bird Hesperornis wandered?

Don’t mess with Hesperornis. It was a flightless, aquatic Cretaceous bird that measured up to six feet long, had a beak lined with sharp teeth, and was partially responsible for the downfall of at least one scientific career*. It superficially resembled … Continue reading »

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Two retractions appear for former Harvard dental researcher found to have committed misconduct

Martin

Martin Biosse-Duplan

Martin Biosse-Duplan, a former Harvard dental school research fellow found by the Office of Research Integrity to have falsified results has had the two papers in question retracted.

From the Journal of Bone and Mineral Research:

The following abstract from the Journal of Bone and Mineral Research supplement, “The Association Between the Microtubule Plus End Protein EB1 and Cortactin Controls Podosomes and Bone Resorption” by Martin Biosse-Duplan, Sebastien Stephens, Frank PL Lai, Margit Oelkers, Daisuke Kitamura, Klemens Rottner, William Horne, and Roland Baron, published online on 17 August 2011 in ASBMR 2011 Annual Meeting Abstracts (ASBMR.org), has been retracted by agreement between the authors, the journal Editor in Chief, Juliet E Compston, the American Society for Bone and Mineral Research, and Wiley Periodicals, Inc.

As a result of a PI-initiated inquiry within Harvard, the U.S. Office of Research Integrity (ORI) has determined that Biosse-Duplan falsified histomorphometric and microCT results.

From Bone:

This abstract has been retracted at the request of Drs. S Stephens, FPL Lai, M Oelkers, K Rottner, W Horne and R Baron. As a result of a PI-initiated inquiry within Harvard, the U.S. Office of Research Integrity (ORI) has determined that Dr Biosse-Duplan falsified histomorphometric and microCT results.

Note that the last lines of both notices are identical (except for “Dr”). Specifically, the ORI had found that Biosse-Duplan:

Falsified Powerpoint slides and spreadsheets for histomorphometric and microCT results by using the values of HS1 knockout (KO) mice and their controls to represent the CathepsinK cre- Cortactin KO mice and their controls; Dr. Biosse-Duplan also switched two sets of numbers between the HS1 KO mice and their controls to falsely demonstrate a difference in bone density when there was none. The numerical data were presented at a lab meeting, and false text was included in two submitted meeting abstracts published in Bone 48:Suppl 2, pS97 and J Bone and Mineral Research 25:Suppl 1, pS215.

The Bone paper has been cited once, according to Thomson Scientific’s Web of Knowledge, while the JBMR paper has yet to be cited.


Former Harvard dental school researcher committed misconduct: ORI

Martin Biosse-Duplan

Martin Biosse-Duplan

Last week was a busy one at the U.S. Office of Research Integrity (ORI), at least judging by how many cases they posted. There were sanctions against researchers at Ohio State, Texas Tech, and the Gladstone Institutes, as we reported. And it turns out there was another case closed, of a former Harvard dental school research fellow, The Scientist reports.

According to the ORI, Martin Biosse-Duplan “engaged in research misconduct in research supported by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), grant R01 AR054450.”

The misconduct involved a lab presentation and two published abstracts:

According to the ORI:

As a result of HSM’s and HSDM’s investigation, the data were not presented at the meetings and the experiments reported in the abstracts are being redone.

Specifically, ORI finds that Respondent:

Falsified Powerpoint slides and spreadsheets for histomorphometric and microCT results by using the values of HS1 knockout (KO) mice and their controls to represent the CathepsinK cre- Cortactin KO mice and their controls; Dr. Biosse-Duplan also switched two sets of numbers between the HS1 KO mice and their controls to falsely demonstrate a difference in bone density when there was none. The numerical data were presented at a lab meeting, and false text was included in two submitted meeting abstracts published in Bone 48:Suppl 2, pS97 and J Bone and Mineral Research 25:Suppl 1, pS215.

Boisse-Duplan has agreed to have any research supported by the Public Health Service — the umbrella agency of the NIH — supervised for two years, and to a two-year ban on serving on NIH peer review committees.