Streamlining Access to SRA COVID-19 Datasets on the Cloud

To make it easier for you to find and access Sequence Read Archive (SRA) data, we are re-organizing and improving our cloud storage systems.   Beginning April 2023, we will move the SARS-CoV-2 normalized data and source files from the COVID-19 data buckets on Amazon Web Services (AWS) and Google Cloud Platform (GCP) to the NIH … Continue reading Streamlining Access to SRA COVID-19 Datasets on the Cloud

Announcing the NCBI SARS-CoV-2 Variant Calling Pipeline and Related Data Products

Still waiting for an analysis pipeline that can uniformly process raw sequence data produced by a variety of sequencing platforms? Your wait is over! Announcing the SARS-CoV-2 Variant Calling Pipeline, which is now operational and optimized to provide support for multiple sequencing platforms including, Illumina, Oxford Nanopore, and PacBio. This new pipeline can make allele … Continue reading Announcing the NCBI SARS-CoV-2 Variant Calling Pipeline and Related Data Products

NCBI Workshop at the ASM NGS 2022 Meeting

NCBI Microbial Pathogen and SARS-CoV-2 Resources in the Cloud Get hands-on experience with NCBI Pathogen Detection and SARS-CoV-2 Surveillance data in the cloud. No prior cloud experience necessary! NCBI staff are presenting a workshop at the American Society for Microbiology Next-Generation Sequencing (ASM NGS) 2022 Meeting on Sunday, October 16, 2022 from 10 am – 3 … Continue reading NCBI Workshop at the ASM NGS 2022 Meeting

Top 3 reasons to use ElasticBLAST

ElasticBLAST is a new way to BLAST large numbers of queries, faster and on the cloud. Here are the top three reasons you should use ElasticBLAST: 1. ElasticBLAST can handle much LARGER queries!  ElasticBLAST can search query sets that have hundreds to millions of sequences and against BLAST databases of all sizes. 2. ElasticBLAST is … Continue reading Top 3 reasons to use ElasticBLAST

Introducing SARS-CoV-2 Variants Overview, NLM’s latest tool in the fight against COVID-19 

The National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM) has released a new resource, called the SARS-CoV-2 Variants Overview, that aggregates data related to SARS-CoV-2 variants from sequences available in NCBI’s GenBank and Sequence Read Archive (SRA) databases. SARS-CoV-2 Variants Overview, a freely available online dashboard, was developed with guidance from the TRACE Working Group as … Continue reading Introducing SARS-CoV-2 Variants Overview, NLM’s latest tool in the fight against COVID-19 

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Tackling Petabyte Scale Sequence Search Challenges

The volume of biological data being generated by the scientific community is growing exponentially, reflecting technological advances and research activities. This increase in available data has great promise for pushing scientific discovery but also introduces new challenges that scientific communities need to address. The National Institutes of Health’s (NIH) Sequence Read Archive (SRA), which is … Continue reading Tackling Petabyte Scale Sequence Search Challenges

The wait is over… NIH’s Public Sequence Read Archive is now open access on the cloud

The NIH NCBI Sequence Read Archive (SRA) on AWS, containing all public SRA data, is now live! This data is hosted on Amazon Web Services (AWS) under the Open Data Sponsorship Program (ODP) with support from NIH’s Science and Technology Research Infrastructure for Discovery, Experimentation, and Sustainability (STRIDES) initiative. The SRA is NIH’s primary repository for raw, … Continue reading The wait is over… NIH’s Public Sequence Read Archive is now open access on the cloud

NIH’s COVID-focused Sequence Read Archive (SRA) datasets are now open access on AWS!

While searching for SARS-CoV-2 sequences, have you longed for a COVID-focused SRA dataset? Great news — now there is one! We are happy to announce the addition of COVID-focused datasets (including source and normalized SRA file formats) to the AWS … Continue reading

We want to hear from you about changes to NIH’s Sequence Read Archive data format and storage

NIH’s Sequence Read Archive (SRA) is the largest, most diverse collection of next generation sequencing data from human, non-human and microbial sources. Hosted by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), SRA data … Continue reading

May 20 webinar: Exploring SRA metadata in the cloud with BigQuery

Join us on May 20th to learn how to use Google’s BigQuery to quickly search the data from the Sequence Read Archive (SRA) in the cloud to speed up your bioinformatic research and discovery projects. BigQuery is a tool for … Continue reading