New download files and FTP directories for genome assemblies

You can now download new file types for species recently annotated by the NCBI Eukaryotic Genome Annotation Pipeline from the Assembly web pages and from the genomes/refseq FTP area. The new files types include alignments of annotated transcripts to the … Continue reading

Coming Soon: A New NIH Manuscript Submission (NIHMS) System!

Reflecting the National Library of Medicine’s (NLM) ongoing commitment to public access support at the National Institutes of Health (NIH) and beyond, we are pleased to announce that a new NIHMS system will be released in early 2020. This new … Continue reading

December 11 Webinar: Running the NCBI Prokaryotic Genome Annotation Pipeline (PGAP) on your own data

On Wednesday, December 11, 2019 at 12 PM, NCBI staff will present a webinar that will show you how to use NCBI’s PGAP (https://github.com/ncbi/pgap) on your own data to predict genes on bacterial and archaeal genomes using the same inputs … Continue reading

December 11 Webinar: Running the NCBI Prokaryotic Genome Annotation Pipeline (PGAP) on your own data

On Wednesday, December 11, 2019 at 12 PM, NCBI staff will present a webinar that will show you how to use NCBI’s PGAP (https://github.com/ncbi/pgap) on your own data to predict genes on bacterial and archaeal genomes using the same inputs … Continue reading

December 4 Webinar: Human population genetic variation data at NCBI

On Wednesday, December 4, 2019 at 12 PM, NCBI staff will present a webinar on the population variation datasets at NCBI such as 1000 Genomes, ExAC, GnomAD, and TopMed that are currently included on dbSNP records. You will learn how … Continue reading

New release of the Prokaryotic Genome Annotation Pipeline with updated tRNAscan and protein models

A new version of the Prokaryotic Genome Annotation Pipeline (PGAP) is now available on GitHub. This release uses a new and improved version of tRNAscan (tRNAscan-SE:2.0.4) and includes our most up-to-date Hidden Markov Model and BlastRule collections for naming proteins. Remember … Continue reading

Pangenome metadata scopeathon in San Diego, January 16-17

We will help run a scopeathon (January 16-17, 2020). This event focuses on planning and designing software to extract value from organismal and genera-level graph genomes by dynamically labeling with metadata. We’re seeking people who are interested in describing community level … Continue reading

NCBI Will Retire the Probe Database in April 2020

NCBI released the Probe database in 2005 as a registry of nucleic acid reagents for biomedical research. At that time array-based assays were prevalent, but have since declined with the advent of short read sequencing. As a result, NCBI will … Continue reading

Request for proposals: Single Cell in the Cloud codeathon at NYGC in January

The New York Genome Center is hosting an NCBI  Single Cell in the cloud codeathon from January 15-17, 2020. Submissions for project proposals are due December 2nd. Please submit your proposal and apply here. What topics are in scope? This codeathon … Continue reading

RefSeq Release 97 is public

RefSeq release 97 is accessible online, via FTP and through NCBI’s Entrez programming utilities, E-utilities. This full release incorporates genomic, transcript, and protein data available, as of November 4, 2019 and contains 219,407,891 records, including 157,639,958 proteins, 28,730,283 RNAs, and … Continue reading